Chemistry Professor Vahe Bandarian is exploring the biosynthetic pathways that are involved in the production of modified nucleic acids, such as those found in RNA.
In fact, RNA is among the most highly modified biological molecules, with more than 100 modifications observed to date. While most modifications entail simple transformations, some are so-called hyper-modified bases where multiple steps are involved. Recent studies point to links between RNA modifications and cellular processes, some of which underlie diseases.
Matthew S. Sigman, Distinguished Professor and Peter J. and Christine S. Stang Presidential Endowed Chair of Chemistry, is helping the U.S. Department of Energy (DOE) develop highly efficient next-generation battery technologies for energy storage.
Sigman and U of U colleague Shelley Minteer, along with University of Michigan chemists, are participating in the Department of Energy’s Joint Center for Energy Storage Research, to develop a better type of battery architecture for grid energy storage called redox flow batteries.
Because the sun doesn’t always shine, solar utilities need a way to store extra charge for a rainy day. The same goes for wind power facilities, since the wind doesn’t always blow. To take full advantage of renewable energy, electrical grids need large batteries that can store the power coming from wind and solar installations until it is needed. Some of the current technologies that are potentially very appealing for the electrical grid are inefficient and short-lived.
University of Utah and University of Michigan chemists, participating in the U.S. Department of Energy’s Joint Center for Energy Storage Research, predict a better future for a type of battery for grid storage called redox flow batteries. Using a predictive model of molecules and their properties, the team has developed a charge-storing molecule around 1,000 times more stable than current compounds. Their results are reported today in the Journal of the American Chemical Society.
Nearly a century ago, German chemist Fritz Haber won the Nobel Prize in Chemistry for a process to generate ammonia from hydrogen and nitrogen gases. The process, still in use today, ushered in a revolution in agriculture, but now consumes around one percent of the world’s energy to achieve the high pressures and temperatures that drive the chemical reactions to produce ammonia.
Today, University of Utah chemists publish a different method, using enzymes derived from nature, that generates ammonia at room temperature. As a bonus, the reaction generates a small electrical current. The method is published in Angewandte Chemie International Edition.
Matthew Sigman, Distinguished Professor & Peter J. Christine S. Stang Presidential Endowed Chair of Chemistry with the University of Utah has been awarded the ACS Award for Creative Work in Synthetic Organic Chemistry, "For his creative, seminal work in synthetic organic chemistry, especially his innovative contributions to the Wacker oxidation and Heck reaction."
More than one million people in the United States develop cancer each year. However, two in every three people diagnosed with cancer today will survive at least five years, thanks to basic scientific research and the tireless work of the American Cancer Society.
Bethany Buck-Koehntop, assistant professor of chemistry at the U, is part of this effort. She is using a multidisciplinary approach of structural biology, biochemistry, molecular biology and cellular biology to investigate the role of certain proteins in DNA expression and regulation within the cell.
Gov. Gary R. Herbert, along with the Utah Science Technology and Research (USTAR) initiative and the Governor’s Office for Economic Development (GOED), announced Thursday the winners of the 2016 Governor’s Medals for Science and Technology. The medals will be presented to 11 individuals and one company at a 30th anniversary awards dinner on Jan. 18.
Scientists from the University of Utah and University of Washington have developed blueprints that instruct human cells to assemble a virus-like delivery system that can transport custom cargo from one cell to another. As reported online in Nature on Nov. 30, the research is a step toward a nature-inspired means for delivering therapeutics directly to specific cell types within the body.
The article shows the first example of capture beads having more than one capture sequence, expanding the ability to study genetic variation and differences in gene expression profiles between cell populations.