Denise Dearing Awarded Governor's Medal


May 7, 2025
Above: M. Denise Dearing

The office of the Governor of Utah announced that University of Utah biologist M. Denise Dearing is this year’s recipient of the prestigious 2025 Utah Governor’s Medal for Science and Technology in the Academia/Research category.

The selection for this significant honor follows a rigorous process involving peer nominations, evaluation by a panel of qualified judges and Utah Governor Spencer J. Cox’s final approval.

“Your outstanding contributions as an ecologist have established a remarkable international reputation for your innovative research and discoveries, and your leadership at both the university and national levels,” Cox states in his official letter to Dearing. “Your pioneering research, program development that benefits the state of Utah, and numerous awards recognizing your international stature embody the excellence in academia/research this medal celebrates.” He also acknowledges Dearing’s “dedication as an effective mentor and teacher, providing exceptional guidance to graduate students and postdoctoral scholars.”

The Governor's Medal is the state’s highest civilian award, celebrating distinguished service and significant contributions to science and technology. Since 1987, this medal has recognized individuals like Dearing, for their impact and achievements.

Dearing will receive the medal at a ceremony on May 21, 2025.

“Being a world-class scientist today requires an extraordinary breadth of skills,” said Fred Adler, Director of the School of Biological Sciences, “and Dr. Dearing has the entire set, ranging from her breadth, creativity and influence as a scientist, her dedicated and innovative teaching, caring and successful mentoring and leadership both at the University of Utah and nationally.”

Woodrats, Toxins and Rattlesnakes

Since 2022 Dearing, a Distinguished Professor in the School of Biological Sciences as well as its former director, has served as the Director of the Division of Integrative Organismal Systems at the National Science Foundation. She and her team study ecological factors and physiological constraints that influence foraging behavior and the evolution of diet breadth in mammalian herbivores.

Currently, her laboratory is investigating the evolution of dietary specialization in herbivores by exploring the detoxification abilities of woodrats (Neotoma species). Woodrats are one of the only animals that can tolerate large quantities of creosote, a shrub with leaves coated in a chemical cocktail of poisonous resin, according to a recent article on Dearing’s research published in @TheU: “The critter’s constitution has astounded biologists and represents a decades-long debate — over evolutionary time, how do animals adapt to a deadly diet? Do detoxification enzymes become more specialized or more abundant?”

In January, Dearing’s team published a landmark paper in the journal Science pinpointing the specific genes and enzymes that allow the woodrats to eat the near-lethal food without obvious harm. They found that creosote feeding woodrats had “doubled down” on detox, having several more key detoxification genes than their counterparts that do not eat creosote.

Dearing’s research has fueled the findings of others, including those presented in a paper published in Biology Letters just three weeks ago. A research team out of the University of Michigan in collaboration with Dearing investigated the immunity of creosote-eating woodrats to rattlesnake venom, a substance that contains hemotoxins that break down blood cells and neurotoxins that cause respiratory paralysis.

Medications like anticoagulants and even Ozempic have resulted from the pharmacologically active molecules discovered in the study of venoms and the animals that resist them. Related to that, coevolutionary relationships between snakes and their prey in one location to another can lead to the discovery of powerful molecules that may have other important applications.

“We are proud to celebrate Denise Dearing’s well-deserved recognition with the Utah Governor’s Medal for Science and Technology,” said Pearl Sandick, interim dean of College of Science. “This award recognizes Dearing’s exceptional contributions to science and technology in the state, and we are thrilled to see her join the distinguished group of individuals who have received this honor. Her work has had a profound impact on our academic community and beyond. Her collaborative spirit and dedication have made her an invaluable scientist and colleague.”

by David Pace