Peptides, composed of amino acid residues, can be designed as therapeutics for the treatment of human diseases. Their smaller size and high design modularity make them attractive scaffolds for drug development. The Roberts laboratory draws inspiration from cyclic peptide natural products that are formed by site- and residue-selective oxidation reactions. We use solid phase peptide synthesis to prepare modified peptides that can be oxidatively modified in solution to access proteolytically stable cyclic peptides. This research opportunity will provide broad training in organic chemistry. You will learn about the structure and function of peptides, train in methods for their synthesis, purification, and characterization, and help our team to demonstrate the scope and therapeutic applications of novel cyclization reactions.