SRI stories:  From the lab to Costa Rica

 

Despite being over three thousand miles away from her lab back in Salt Lake City, Sylvia Lee was still able to sequence the DNA of the species she is studying.

While doing field work in Costa Rica, Sylvia continued her research by using Oxford Nanopore’s MinION, a portable technology that allows for DNA and RNA sequencing wherever you are.

Sylvia works in an SRI research stream that focuses on using Next Generation Sequencing (NGS) technologies to barcode and sequence DNA. This allows her lab to uncover new species and their phylogenetics. NGS allows in-house sequencing within the lab, rather than having to send it off to a company or lab. Or with the portable MinIOn, on a Costa Rican beach.

Sylvia’s main project is focused on ant-plant symbioses. She works to identify a third party within that symbiosis which is a crucial piece of the mutualistic interactions between ants and plants. The ants can’t get certain nutrients from their host plant, so the third party, mealybugs, are essential for this mutualistic relationship. She’s identifying the species of mealybugs involved, and after that, will look more closely at the nitrogen-fixing microbiome surrounding this entire process.

Sylvia is planning to go to graduate school, pursuing research in the biotech field. She’s a Social Justice Advocate, connecting U housing residents to resources and creating safe communities where they feel like they belong. She’s also part of the U’s undergraduate chapter of SACNAS, designed to support Chicano, Hispanic and Native American STEM students. 

“My parents are my heroes,” she said. “I look up to them because I have seen how much they’ve gone through, raising two children in a foreign country, far away from what’s familiar and far from where they called home. They did all of this just to make sure their kids would have a good life and a good future.”

Sylvia was born in Cheongju, South Korea, but at a young age moved overseas with her family. She traveled many places, but spent a lot of time in Mexico, and came to the U as an international student. Sequencing DNA has not only proven “portable” for Sylvia Lee; when she graduates with BS in biology and minor in chemistry, they’ll be infinitely “portable” as well. 

By CJ Siebeneck