Ryan J. White ’07 Chemistry

Ryan J. White '07, Chemistry

 

University of Cincinnati's College of Arts and Sciences has announced Ryan J. White as the new divisional dean of natural sciences.

The inclusion of the alumnus from the University of Utah (chemistry) will bring new focus and structure around student success and the college of Arts and Sciences’ advancement. White, who as a candidate for his PhD with Dean of the College of Science, chemistry professor Henry White, will officially begin his new term on Jan. 1, 2024.

“My vision for the Division of Natural Sciences in A&S is to continue to grow each unit as leading departments in the US by sustaining our current strengths in research and education, while cultivating our division’s culture of commitment to diversity, equity, inclusion, belonging, and student success,” said White.

Given his tenure as an educator in the department, White has had ample time to observe the strengths of the natural sciences division and areas of potential.

If I could have two dream opportunities to kick off my time in this role, it would be the development of a creative incubator space to help launch innovative new research and training programs and to develop programs that holistically support student success in STEM disciplines,” said White.

However, this position was not always the forefront for White, and still remains secondary to his goal as an educator and innovator.

“Becoming a divisional dean was only peripherally in my vision early in Fall 2023. However, the opportunity to work with the college leadership was an opportunity that excited (and still excites) me,” he said. “The position also provides unique opportunities to think about ways that the natural sciences can interact and collaborate with the social sciences and humanities and provide holistic training and educational opportunities for our students and scholars.”

White is an Ohio Eminent Scholar and has served as the Head of Chemistry since Fall 2022 with a joint appointment in the Department of Electrical and Computer Engineering. He earned his bachelor’s degree in chemistry from the University of North Carolina in 2007, to then complete his education with a PhD in chemistry from the University of Utah in 2007. Following his NIH NRSA postdoctoral fellowship at UC Santa Barbara, he began teaching chemistry and biochemistry at UMBC in 2011. White made his way to UC in the fall of 2017.

SRI Stories

SRI Stories: Turning student researchers Loose

 

Mosquitoes, those pesky little aviators we spend a lot of time swatting at, are pesky for two reasons: they carry diseases, like malaria–true–but they are also guilty of harassment.

Chris Bibbs, Great Salt Lake

Yes. Harassment, regardless of how you pronounce the word, will get you in trouble by your local mosquito abatement district (appropriately acronym-ed as “MAD”). It turns out that the pest in “pesky” can actually have a deleterious effect on lifestyle, kids walking to and from school, vacationers and can even, eventually, impact the local economy.

Whether it’s dodging dengue or out-maneuvering the little dogfighting Red Barons as you try to conduct business, Salt Lake Valley has one of the first MADs in the country, predating the Center for Disease Control and Prevention known for its recent flurry of COVID-19 mandates by more than twenty years.

And Salt Lake City MAD (SLCMAD), located north of the airport down on the floodplain by the Great Salt Lake, is also the catalyst for one of the Science Research Initiative’s (SRI’s) celebrated research streams that science students can participate in.

Ready to get bitten by the bug of composite biology research? You’ll be in good hands. Toxicologist and behavioralist Christopher Bibbs, SLCMAD’s laboratory director, and SRI stream leader with his colleague Nate Byers and others can take you the distance into the fascinating world of mosquitos as they interface with public health and environmental concerns.

“Although our job is to deal with the mosquitoes, we coexist with this entire system,” says Chris, meaning that scientists don't just survey only those of us with a blood-flush target on us. “We look at non-targets; we look at migratory bird pathways; we look at invasives; we look at general composite biology.” To work in abatement doesn’t just mean you’re a mosquito murderer–fly swatter in hand or the wielder of broad-spectrum pesticides, which do not discriminate what they kill; you have to be concerned about the types of interventions you experiment with.

“If you introduce this into the system, does it cause harm?” Chris is quick to ask. “If we use a pesticide? Does it create a pollution build–up? If we use a trap, does this give a reasonable inference on what's going on in the area? We do all these types of exploratory projects, because again, the goal is to help track and control mosquitoes. So, any discipline that we can use, whether that's biochemistry, bioinformatics, spatial modeling, whatever — engineering — it's a tool for us.”

Under the direction of molecular biologist Nate who sets up the traps — 60 at a time — team members do viral surveillance looking for viruses in field-caught mosquitoes. This is followed by collating and analyzing data. Research at SLCMAD presents a field as well as a lab component to the experience. And the work is not only ultimately a public service but the process sets up an exploratory site emblematic of the kind of pure science inquiries that undergraduates are asked (and encouraged) to do at the University of Utah.

Indubitably, sheer curiosity drives the research.

Past students during the spring semester (2023) stream were not just dodging bites by female mosquitoes (the ones who need a blood meal to produce eggs). No, these SRI students were asking questions and setting up experiments that helped vector the SLCMAD team in different but productive research directions, something SLCMAD is eternally grateful for.

“The stuff that we're doing isn't just some fundamentalisms about the fields,” says Chris, who has a lot to say about his work as SRI stream leader and preceptor with the U students and other interns. “It's stuff that can actually help people, maybe change a process, maybe improve the way you look at data. Maybe it's just a new method of doing something, designing equipment, new traps, or something like that. So, this is the kind of stuff that's actually very easy to get out there. Because it's tangible and useful to people. So that's something I can pretty reliably offer.”

Chris and his team are relatively regimented in their mentoring. “I try to figure out what you like,” says Chris, referring to his mentees. “It's not even what you've been trained in. What do you like, right now? What are you interested in? What do you want to do? And I try to take those interests and piece them together with stuff that we have already talked about that we would like to do.” This is followed by a review of the research literature and then, says Chris, “I kind of turn you loose.”

The result has been gratifying. Students have come to him with ideas–sometimes that make him raise an eyebrow–but that ends up productive, like looking at how common synthetic sugar additives trigger forceful hypoglycemic reactions that are toxic to mosquitoes. Or, like the freshman student who kept bringing up the component of vision in the animal which is typically thought to be olfactory driven. “He was absolutely right,” says Chris, of the student whose findings from bio assays were eventually paired with research being done by biology professor Neil Vickers who is on the SLCMAD board.

“On top of that,” continues Chris, “for us as a district, you know, [this student’s work] pertained to a mosquito that actively harasses people all year long.” Now, the District is planning on using this information to attempt better surveillance on the species which, if left unchecked, can cause heart-worm disease in domestic animals like cats and dogs.

But wait. There’s more!

Both of these research questions led to experiments, data, conclusions and eventually a paper–more than one. (Not a bad thing to publish papers as an undergraduate. You can read one of these papers co-authored by undergrad Irvane Nelson here.)

“I'm super proud of the SRI involvement with this, because I kind of went into this not knowing what to expect, but I feel like with their unique creativity, and how they look at stuff, they really contributed a lot to this whole equation. It's kind of funny [the process], but it's like now … you were on the money!”

There’s something infectious, no pun intended, about Chris and Nate’s animated descriptions of what might appear as an unlikely marriage of an entity whose main goal is public health with an auxiliary function of research with an SRI teaching lab at the U. Part of that elevated feeling is likely that, to do their mission-driven job, MAD deploys every aspect of biology, ecology, chemistry, physics, and “every nuance and subdiscipline” to get the job of mosquito abatement done.

It’s a model for targeted, real-work experience connected with academics and research, and — except for the mosquitoes — everyone, especially SRI students, seem to benefit.

By David Pace

SRI Stories is a series by the College of Science, intended to share transformative experiences from students, alums, postdocs and faculty of the Science Research Initiative. To read more stories, visit the SRI Stories page.

Nematode proteins shed light on infertility

Nematode proteins shed light on infertility

 

We have two copies of each chromosome in every cell in our bodies except in our reproductive cells.

 

The Rog Lab

Sperm and egg cells contain a single copy of each chromosome with a unique mix of genes from our parents, an evolutionary trick to give our offspring genetic variability. The sperm and egg are made during meiosis, the process by which cells with two chromosome copies reduce their chromosome numbers to one. For meiosis to work, the two chromosomes must align perfectly and exchange the correct amount of genetic information. Any deviation puts fertility at risk.

Enter the synaptonemal complex (SC), a zipper-like protein structure that lines up and anchors the two parental chromosomes together, end-to-end, to facilitate successful genetic exchanges. Failure to regulate this exchange is a leading cause of age-related infertility in humans and could compromise fertility across the tree of life. Humans, fungi, plants, worms and anything that reproduces sexually uses the SC to make reproductive cells, known as gametes. Despite its importance, we don’t understand how proteins within the SC regulate chromosomal interactions because this multi-step process happens in internal organs and has been impossible to recreate in a lab.

“This is a way to lock in on systems in cells that are too ‘loosie-goosey’ to use methods that rely on crystallization,” said Ofer Rog, associate professor of biology at the U and senior author of the study. “A lot of the interactions in cells are loosely bonded together. The problem is that you can’t look at it under an electron microscope because nothing is stable enough—everything is constantly moving. Our approach allows you to study even the interactions that are relatively weak or transient.”

 

Read the full article by Lisa Potter in @TheU

Humans of the U: Ramón Barthelemy

“Ideas of social justice, inclusion and equity have always been at the forefront of my mind.

I’m a first-generation in an immigrant family and this has given me a perspective that most other people in physics don’t have. I noticed that there was a trend in who was in the field, with fewer underrepresented and minoritized students and faculty, and this trend had been confirmed by the data. This is something that caught my attention and I got really excited about how we can change this trend to make physics more inclusive. So, when I started my Ph.D. program, I actually switched from nuclear physics to physics education research and started pursuing this line of inquiry. The reason why this work is needed is that physics is incredibly challenged with representation and the experiences of individuals in the community.

I believe my presence adds to the field of physics scholarship. I don’t use deficit language and I don’t use comparisons when talking about marginalized groups. Making these comparisons is inequitable because you’re defining what is ‘normal’ in one group and saying that the other group should be compared to that normal. Instead, we should talk directly to the people being impacted and learn from their experiences to craft policy in order to make a change in the field.

One of the biggest findings that we’ve had is that inclusivity in physics is much more predictive of people staying in the field than exclusivity is predictive of people leaving. What that tells us is that inclusion is a more powerful experience than discrimination. When we think about the climate of physics, a neutral climate is not enough. We have to create an actively inclusive climate if we want to make a change in this field and make sure that everybody is fully included.

I would love to see a physics community that anybody can come to and participate in. I want them to be able to bring their background, their unique perspective and their full self to physics.”

– Ramón Barthelemy, assistant professor, Department of Physics & Astronomy

This story originally appeared in @TheU.

Humans of the U: Sadie Dunn

“I am currently majoring in atmospheric sciences. I just love weather. I’ve loved it since I was probably in kindergarten. So growing up, I always knew that was what I was going to study in college. When I was looking at colleges, I was kind of shocked that the University of Utah is the only school in Utah that offers an atmospheric sciences degree. So that’s how I ended up here.

The For Utah Scholarship has been an amazing opportunity for me because honestly, I would not have been able to afford college on my own. This scholarship offered me the amazing opportunity to come and study here in the department I want to be in.

I am from Chicago and I grew up with really severe summer storms in the Midwest, so I guess that’s what really fostered my love for weather. Then I moved to Utah when I was 13 and just kept loving weather. There’s a ton of snow out here and crazy windstorms which sparked my curiosity.

All throughout junior high and high school, I knew studying weather was my goal. So when I was a senior in high school, we had an internship class and I got to intern at ABC 4 news in their weather department, which was cool. That was definitely the moment when I was like, ‘This is real. I’m working towards this and this is the goal.’ So it’s really exciting to take this love I’ve had since I was little and turn it into a career.

While interning at a broadcast station was fun, it’s not something that interests me as a career. But my atmospheric sciences degree can take me a bunch of different places. It offers research opportunities with organizations like the National Weather Service and the National Oceanic and Atmospheric Administration (NOAA). You can also work with private organizations. There are serious meteorologists in every field, which I think is one of the coolest parts about this job.

I’m still kind of feeling out what I want to do. It’s a STEM major and it’s very math- and physics- and chemistry-heavy. I consider myself to be smart, but I am not a natural in those courses. So I don’t think research is something I will do. I am really passionate about climate change, so I’m looking more into the field of sustainability.

Since I grew up with a love of severe weather, I would also love to be able to get a career that helps with the effects of those disasters, because it’s hard with hurricanes and tornadoes. You can’t stop them. They are going to hit and destroy everything. So I would love to find ways to lessen the effects of those or find better ways to prepare the communities.”

—Sadie Dunn, recipient of the For Utah Scholarship

This story originally appeared in @TheU.

Remembering Geologist Hellmut Doelling

Geology alumnus and generous donor, Hellmut Hans Doelling, worked as a core laboratory curator, draftsman, and assistant geologist with the Utah Geological and Mineral Survey (UGMS) before returning to the U to earn his PhD in geology. 

He was born on 25 July 1930 in Richmond Hill, Queensborough, New York City, the only son of Otto Johannes Doelling and Emma Camilla Hartmann.  The family moved to Salt Lake City in 1943 and crossed “the plains” on a Greyhound bus in 5 days due to a 35 mph speed limit during WWII.

Doelling graduated from West High School in 1948, lettering in track and field. He attended the U from 1948 to 1950, then received a letter from Harry Truman and served in the U.S. Army from 1951 to 1953 during the Korean War, returning to the U in 1953 where he graduated with a B.S. in Geology. He was then called on a mission for the Church of Jesus Christ of Latter-day Saint to the East German Mission, where he served in Neumünster, Brake/Weser, Uelzen, and Berlin, under Presidents Gregory and Robbins. Work experiences up to this time included fruit picker, farmhand, paper delivery boy, newspaper inserter, copy boy, and photo lab assistant (Salt Lake Telegram and Tribune).

After earning his PhD, Doelling first taught at Midwestern University in Wichita Falls, Texas, 1964 to 1966, keeping ties with the UGMS in the summertime and was later recruited as the first chief of the Energy and Minerals Section. In 1983 he became the first chief of the Geologic Mapping program, a position he held until 1995. He then continued as a senior geologist until his formal retirement in 2003. 

Highlights of his profession include the publication of more than 200 books, maps, and articles about the geology of Utah. He also served as president of the Utah Geological Association in 1990 and received the Governors Medal for Science and Technology in 1993.  He also did consulting work, mostly in the western states: in Colorado, Nevada, Arizona, Oregon, California, and New Mexico. He also worked in Arkansas, Mexico, and Canada. 

Doelling also did consulting work, mostly in the West. He also worked in Arkansas, Mexico, and Canada. A gifted musician on the accordion, piano, harmonium, and organ, he died 29 November 2023 in Centerville, Utah at the age of 93. He was born  survived by his wife, Gerda and their seven children.

The Doelling Endowed Scholarship  in the U’s Department of Geology & Geophysics, is named in his honor. 

Read Dr. Doelling’s obituary here

Presidential Scholar Award

Presidential Scholar Award

Associate Professor of biology Sophie Caron is a 2023 awardee. The University of Utah Presidential Scholar Award supports the work of exceptionally promising mid-career faculty in academic units across campus by providing $10,000 in funding each year for three years to the award winners.

 

In addition to Caron, an internationally prominent neuroscientist, other awardees include a top researcher in prosthetics, an expert in environmental health and public health challenges and a distinguished leader in the field of chronic diseases in vulnerable populations have been selected as the 2023 cohort of Presidential Scholars. The associate professors will receive this designation for three years.

The Presidential Scholar award supports the work of exceptionally promising mid-career faculty in academic units across campus by providing $10,000 in funding each year for three years to the award winners. The funds — made possible by support from a private donor — may be used to support scholarly, teaching and outreach activities. Up to four new Presidential Scholar Awards are made each year.

Former Mario Capecchi Endowed Chair, Caron uses cutting-edge techniques to tackle fundamental questions about perception. In order to understand how brains are built to learn, she uses the Drosophila mushroom body as a model system. She built an interdisciplinary research program by drawing on computational models, species-comparative studies and various anatomical, functional and behavioral techniques to elucidate the structural, functional and evolutionary pressures that shape the mushroom’s learning function. For her work, Caron has received an NSF CAREER award and two NIH R01 awards, totaling $4.5 million. In addition to her research, Caron designed and regularly teaches the popular cellular neurobiology class (BIOL 3240) which regularly attracts nearly 100 enrollments per semester. Her work has been described as “stunning” and “breathtaking” by colleagues at outside institutions.

In addition to Caron, the 2023 winners include Nancy Allen, associate professor in the College of Nursing; Tommaso Lenzi, associate professor in the Department of Mechanical Engineering in the John and Marcia Price College of Engineering; and Neng Wan, associate professor in the Department of Geography in the College of Social and Behavioral Science.

“These educators represent the cutting-edge work on this campus that can impact our world for the better,” said Mitzi Montoya, senior vice president for academic affairs. “I’m grateful for their contributions and pleased to recognize their research.”

 

Read the full article about all four awardees in @TheU