Andy Thliveris: Remember the Undergrads

Andy Thliveris: 'Remember the Undergrads'

 

In December 2022, Andrew Thliveris BS’83 made a special trip to Salt Lake City with his wife Lauren. They joined the School of Biological Sciences in a belated (due to the pandemic) remembrance of K. Gordon Lark who had passed away more than two-and-a-half years earlier in April 2020.

Vice Chair and Ophthalmology Residency Training Program Director at the University of Wisconsin-Madison’s Department of Ophthalmology and Visual Sciences, Thliveris, until his retirement in September, was also Chief of Ophthalmology at the W.S. Middleton VA and holds the rank of Professor at the School of Medicine in Madison. At the event “Andy” remembered that as an undergraduate he worked in the Lark lab for five years and that Lark had a profound impact on him. “He changed my life,” reported Thliveris whose main message to the faculty and friends who had gathered was “Remember the undergraduate students.”

Thliveris also surprised many by announcing that through his affiliation with the Carl Berg Foundation he had arranged to fully fund the Lark Endowed Chair with a check for $430,000. The Lark fund was established in 2017, followed in July 2022 with a campaign to “re-boot.” The ambition was to achieve the level of endowed professorship through an anonymous, matching donation of $250,000. But with Thliveris’ brokered gift—added to many others from generous individual donors—the K. Gordon Lark Endowment was elevated to the more prestigious level of endowed chair.

'Get this guy under control'

K. Gordon Lark. Credit: Ben Okun

With his characteristic humor, Thliveris was eager to recall his time in Lark’s lab.  He confessed to being that “pesky nerdy undergrad, high-maintenance, known to call Gordon at 11 pm on several occasions, [until] finally, Gordon, then speaking to his post-doc Paul Keim, [said], ‘You’ve got to get this guy under control because I have no idea what the hell I told him last night.’”

Lark wasn’t the only one who mentored, managed and otherwise inspired that “pesky” undergrad. Addressing Nobel laureate and Lark colleague Mario Capecchi who was at the event as well, Thliveris remembered how “you spent many hours with me in your office when you taught biochemistry. I was always in there.” He also recalled Baldomero “Toto” Olivera and his amazing cone snails which would later prove critical in the advance of alternatives to opioid pain relievers, as well as the late Naomi Franklin who helped bring sequencing to Lark’s lab and its occupants.

Regarding Martin “Marty” Rechsteiner, now in the U’s  Spencer Fox Eccles School of Medicine, Thliveris recounted his professor “who on the first day of his class of trembling undergrads told us that if we memorized every word out of this mouth then we might just pass his class.”

Clearly, Thiliveris’ sojourn at the U as an undergraduate where he majored in biology and geology & geophysics, and later attended the U’s medical school where he earned his MD, prepared him well. Following his ophthalmology residency at Wisconsin in 1998, he was a postdoctoral research fellow as a launch to his auspicious 28-year career. After joining the faculty in 2000, he took on the position of Veterans Affairs Hospital service chief and later, in 2014, vice chair of resident education and residency director  — roles he held until his retirement and during which time he trained countless physicians, including many of the department’s own faculty.

'Ball of energy'

At the announcement of his retirement, Thilveris said, “Our residents are beyond amazing, and the dedication from the faculty to our program has made short work for our education team. We have a very proud tradition here and are poised to continue for generations to come.” In hearing the news, many in Wisconsin responded with memories of his meticulous teaching, patience, wisdom, and, of course, his delightful sense of humor.

“I am beyond grateful to Andy for his role in my own training and in my recruitment back to UW-Madison,” said Evan Warner, MD. “His kindness, openness, and genuine concern for each and every colleague, trainee, and staff member has been foundational to our department culture, and it is such a privilege to be a part of it. As residency program director, he has been a ball of energy with so many ideas and such passion for seeking feedback and making things better for the residents.”

Phaco Course Directors Andrew Thliveris, MD, PhD, Sarah Nehls, MD, and Daniel Knoch, MD. (Photo © Andy Manis)

Thliveris will also be remembered for his work as director of the department’s cataract extraction phacoemulsification course. In this three-year progressive course, medical and veterinary ophthalmology residents, UW and visiting medical students, and pre-residency fellows from around the country learn the latest cataract surgical techniques. Daniel Knoch, MD who will assume the role of veterans affairs service chief following Thliveris' retirement recalled how “There are dozens of residents, numerous faculty, and thousands of patients that Andy has helped through his after-hours videos, toolbox approach to surgical teaching, probing questions, and high standards.” Anna Momont, MD who has assumed the role of ophthalmology residency training program director acknowledged that because of Thliveris’ “unwavering dedication to our residents and their training,” is leaving the department nationally recognized and a “highly sought-after residency program.”

'Full steam ahead'

To recognize Thliveris’ lasting legacy, the department dedicated its new Surgical Skills Training Facility in his honor. The new space, which expands the department’s training capacity by providing 10 training pods, each outfitted with state-of-the art equipment, will be instrumental in training the next generation of eyecare specialists. “While the decision to retire was a very emotional one,” says Thliveris, it comforts me greatly to know that I am leaving things in such capable hands. Full steam ahead.”

Whatever Gordon Lark said during those 11 pm phone calls to Andrew Thliveris must have been spectacular. And now with the K. Gordon Lark Endowed Chair poised to announce its first recipient soon, the undergraduate has made sure the legacy of founder of the School of Biological Sciences will continue.

By David Pace

Read more about Dr. Thliveris' retirement at UW-Madison website from which some of this article and photos were taken.

A warming climate could make cities even less hospitable to wild mammals

urban wildlife In a Warming Climate

 

Human-driven climate change could worsen the effects of urbanization on native wildlife, suggests new research based on analyses of data recorded by 725  trail cameras set up in and around 20 North America cities, including Utah’s urban areas along the Wasatch Front.

 

Austin Green, Postdoctoral Fellow in the Science Research Initiative. Camera trap photo above credit: Austin Green.

The main finding was that urbanization’s negative effects on wildlife are tougher on larger-bodied animals and are worse in the less vegetated cities in drier regions, such as Phoenix and Salt Lake City, according to University of Utah wildlife biologist Austin Green, one of the study’s many coauthors.

“Those cities that don’t have as much rainfall have higher average temperatures, the effects that they had on wildlife were greater than in cooler and wetter cities,” Green says.

These findings are based on thousands of photos of wild animals, namely 37 species of native mammals that live in or near cities, ranging from squirrels to black bears. The images were recorded by motion-triggered camera traps operating in the summer of 2019 in places used for outdoor recreation within cities and up to two kilometers beyond the urbanized boundary. To ensure privacy, images of people were automatically deleted by the program that uploaded the photos, according to Green who is aa postdoctoral fellow in the College of Sciences' Science Research Initiative.

Led by Arizona State University biologist Jeffrey Haight, the study published Monday in the journal Nature Ecology & Evolution.

Haight and collaborators from around the country analyzed data from 725 camera traps to assess the composition of native mammal communities and the relative occupancy of each species. In partnership with the Urban Wildlife Information Network, the team covered Salt Lake City, Chicago, Los Angeles, San Francisco Bay Area, Atlanta and Austin and Edmonton in Canada and 13 other cities in the course of some 20,000 camera days.

Read the full article by Brian Maffly in @TheU.

More about this research from the New York Times.

Spiders and Plants, Richard Clark

how spider mites quickly evolve resistance to toxins

Although mites are arthropod-like insects, they have eight legs and are more closely related to ticks, spiders and scorpions. The two-spotted spider mite is tiny, hardly half a millimeter long, and is named for the pair of black spots on either side of its partially translucent body. These spots are actually the digestive contents of its gut.

 

A ubiquitous inhabitant of greenhouses across the United States, it is equipped with needlelike mouthparts that both pierce and suck nutrients from leaves, leaving them a desiccated shell and killing the plant. They also deposit a silky webbing across the host plant, hence the second half of this mite’s common name.

“Arthropod pests have been responsible for historic famines and food shortages, and continue to impact human welfare today by reducing crop yields. So there’s been an interest in developing plant varieties which are more resistant to insects or mites,” said Clark, a professor in the School of Biological Sciences.

Working with then-U graduate student and lead author Meiyuan Ji, as well as colleagues from Belgium, Clark’s lab identified a mechanism by which spider mites “express” genes involved in the detoxification [inactivation] of xenobiotics, as is commonly observed in pesticide-resistant spider mites, according to research published this month. The findings could help scientists develop more effective ways to control this pest.

Read the full story by Brian Maffly on this research in @TheU. 

What the inspiration for ‘Treetop Barbie’ thought of the ‘Barbie’ movie

What the inspiration for ‘Treetop Barbie’ thought of the ‘Barbie’ movie

The canopy scientist (a.k.a. "TreeTop Barbie") and emerita professor of biology at the University of Utah talks about her unusual connection to the iconic doll.

 

Margot Robbie in Barbie. PHOTO: JAAP BUITENDIJK/WARNER BROS.

Nalini Nadkarni, professor emerita of biology at the University of Utah, recently took a trip to the Pacific Northwest — a combined trip for research, visiting friends and making her annual solo backpacking adventure.

There was one more item on Nadkarni’s agenda: Seeing “Barbie,” the hit movie by director Greta Gerwig, based on the long-popular Mattel doll.

“Generally, I felt that it provoked reflections on how we see ourselves and each other; how difficult (perhaps impossible!) it is to define ourselves; and the importance of providing models and choices about our future, without encumbering them with expectations,” Nadkarni wrote in an email. “I felt that many of these messages were presented in the film – not always neatly and coherently, but then, defining oneself is never neat or coherent.”

For Nadkarni, a pioneer in the field of studying the canopies of forests, the connection to a 12-inch plastic figure may not be obvious. It helps to know that when the “Barbie” movie marketing says “she’s everything,” Nadkarni is one of the people who helped make that literally true.

Two decades ago, Nadkarni proposed to Mattel that they create “Treetop Barbie” — a doll with the job of a canopy scientist, a relatively new field at the time. Like Nadkarni, this Barbie would be equipped with the tools necessary to research in the highest part of the forests.

Two decades ago, Nadkarni proposed to Mattel that they create “Treetop Barbie” — a doll with the job of a canopy scientist, a relatively new field at the time. Like Nadkarni, this Barbie would be equipped with the tools necessary to research in the highest part of the forests.

Read the entire article in the Salt Lake Tribune

 

Nalini Nadkarni: Bright Red Arrow

When the ‘Bright Red Arrow’ turns Earthward

 

“[P]retty much all my adult life I’ve been on what I think of as riding this bright red arrow that will take me higher and faster and better with more achievements and more accomplishments, so that people will think, Oh my God, she’s really hot, she’s really worthwhile.”

That’s how Nalini Nadkarni, professor emerita of biology at the University of Utah, describes what it was like before the 50-foot fall she took in Washington state seven years ago. The forest ecologist has been called the “Queen of the Forest Canopy” because of her foundational work in the ecosystems found in the tops of trees, whether in the Northwest or in the tropical clime of Costa Rica. But following her accident in which she was severely battered — including a broken pelvis, ribs and five vertebrae “exploded” — it was, needless to say, a seminal moment in her life.

“Over the weeks, my graduate students visited me,” she says of her stay in the hospital. “I had all kinds of friends who visited me, colleagues came, and I realized that one of the most critical things in recovery. Whether it’s an accident like mine was, or whether it’s the loss of your pet, or whether it’s a heart attack of your neighbor, or whether it’s a broken engagement, what matters most is the web of relationships that you have that carries you through.”

In a recent podcast, Nadkarni talks about her experience. “When I meet someone who’s had a disturbance of some kind, yes, you have to take in the hard parts of that, but there are some generative things about that, and you’re gonna be arriving not at the original state you were, and you’re not gonna be at the disturbed state that you were. You’re not gonna be crumpled on the forest floor, but you’re never gonna get back to that original state, and that’s OK.”

“I’m a better person because of it.,” she concludes. “So I have to, in some ways, thank that rope that failed, that brought me from the canopy to the forest floor. Now, I’m walking again in the new world that I find myself in.”

Listen to the podcast on the Daily Rally above, and read the transcript of the podcast, edited for length and clarity, in Outside magazine.

Gadusol: A More “E-fish-ent” Sunscreen

Gadusol: A More “E-fish-ent” Sunscreen

 

 

As temperatures rise, and outside activities become more popular, many people are thinking about protecting themselves from sunburns and melanomas, primarily using sunscreen.

Marlen Rice. Banner Image: Jamie Gagnon and Marlen Rice. Credit: Todd Anderson

 

However, humans aren’t the only species that have to worry about UV damage. Many species use sunscreen, but not the white lotions that humans are familiar with. Their sunscreens are coded in their DNA. The recently published paper: “Gadusol is a maternally provided sunscreen that protects fish embryos from DNA damage” is the culmination of years of research by University of Utah School of Biological Sciences graduate student Marlen Rice and Assistant Professor of Biology Jamie Gagnon

Gadusol is a chemical sunscreen that is found in the eggs of many fish species. The molecule was discovered in fish over 40 years ago, and was originally thought to come from dietary sources, but it has since been proven that gadusol is produced from a sugar intermediate in one of the metabolic pathways within the fish. The mother deposits the chemical into her eggs as she lays them to protect her babies from the sun. 

Rice grew up on a farm an hour south of Salt Lake, and attended Utah State University where he received a bachelor’s degree in molecular biology. He has always been interested in how animals develop in relation to the world around them. Rice says “The fun thing to me about biology is just the fact that [living] things are dynamic and they interact [with] their environment… I like thinking about animals in relation to ecology. I want to try to bridge those two gaps — the molecular field with ecology.” Rice’s lifelong passion for animals and his industry background inspired him to use laboratory tools to investigate ecological factors, starting with the sun.

 

UVR Exposure

Nearly all life on Earth has an important relationship with the sun, whether that be by using the energy from it to produce food, or consuming other organisms who do. This comes with the cost of extensive exposure to ultraviolet radiation (UVR). UVB rays are the specific wavelengths that are especially dangerous to living organisms. UVR damages proteins and DNA on a molecular level. This damage leads to mutations in DNA, and excessive levels of UVR exposure can even induce apoptosis or cell death, producing what we know as a sunburn. 

According to the paper, “[s]unscreens absorb UV photons before they penetrate vulnerable cells and dissipate this absorbed energy as less harmful heat.” Sunscreens act as physical shields over precious genetic material in cells, preventing damage and mutations. Even in the water, not all aquatic organisms are safe from UVR exposure because biologically harmful levels of UVB can penetrate over 10m deep in clear water. Organisms across many habitats have developed adaptations including nocturnal lifestyles and DNA repair mechanisms to help avoid and fix the problems associated with UV exposure. Furthermore, “since sunlit habitats can have significantly nutritive advantages over dark environments and because no repair pathway is completely efficient, many organisms employ sunscreens to avoid UVR damage from occurring in the first place.” 

Initially, Rice only looked at melanin as the primary sunscreen in aquatic life. In fish, melanin is produced in melanophores that migrate to cover aspects of the brain and body as the fish matures. What he found was that zebrafish embryos were dying from UVR exposure at the same rate, regardless of whether or not their genotype was altered to knockout the gene for melanin production. It became clear that there was something else protecting the embryos. 

Zebrafish

Two-day-old zebrafish. Credit: Marlen Rice

Rice created gadusol-deficient mutant zebrafish through CRISPR-Cas9 gene editing to test gadusol as a sunscreen. Zebrafish were chosen for these experiments because they naturally live in sunlit waters, produce gadusol and are amenable to genetic manipulation. He determined that gadusol is provided for zebrafish embryos by the mother, is the most effective sunscreen over other methods of protection and is lost evolutionarily in fish species when their embryos are not exposed to sunlight.

To show gadusol’s importance, Rice delivered precise doses of UVB to both the wildtype and mutant zebrafish embryos and measured the effect on swim bladder inflation. When exposed to the same dose of UVB, the gadusol-deficient mutant fish were all unable to inflate their swim bladders, indicating that the UV exposure had caused significant developmental defects. This experiment demonstrated that gadusol is critical for the survival of embryonic and larval zebrafish exposed to UVR. 

Fish have been benefiting from gadusol for eons, but in the future, humans could too. Gadusol Laboratories, started at Oregon State University, has been acquired by Boston-based beauty company Arcaea. Their research focuses on synthetically producing gadusol to create sunscreens that would be safer for both humans and the ocean. 

For fish, gadusol offers a tremendous advantage over other sunscreens due to its invisibility. “Transparency as camouflage,” they write, “is a common trait in aquatic animals, especially in the open ocean where there is nothing to hide behind.” This is one of the largest drawbacks for melanin: since it absorbs most wavelengths in the visible light spectrum as well as the UVB spectrum, it is detectable by predators. 

The Beauty of DNA

The sun is just one of the unique ecological challenges that aquatic ecosystems pose to their inhabitants. Gagnon says, “you sort of forget they actually evolve out in the world, [a] very challenging world full of pressures on their survival. …  The environment that they evolved in, which is filled with sunlight and viruses and predators and temperature switches and all this crazy stuff that doesn’t happen in our fish facility, and so if you can bring a little bit of that into our laboratory, now we can apply what’s cool to more questions.” 

These environmental factors will inspire their research with zebrafish moving forward. Rice is also curious about the evolutionary history of gadusol itself. He says, “I’d really like to fill out on the tree of life how widespread gadusol is. And another thing I’m really interested in thinking about is, it seems like at some point, land vertebrates stopped using gadusol. I think evolutionarily it’d be really interesting to think about that. At what point did they move away?”

The answers to these mysteries lie within — within DNA to be specific. Rice says “I really do love the idea of DNA. I think it’s a really beautiful thing … . The fact that it’s an unbroken chain of DNA replication and now lives inside of you.” It will be the combination of molecular biology tools and ecological inspiration that translates the evolutionary history written into the genetic code for all living organisms. 

By Lauren Wigod

Read a first-person account from a zebrafish in Animals of the U: Zippy the Zebrafish.

Sandra J. Bromley Scholarship

 

Sandra J. Bromley Scholarship

Providing a Role Model for New Generations

Ray Greer. Banner Photo above: Dannon Allred, Ray Greer and his wife Jill, Michaela Fluck, Keegan Benfield, Eliza Roberts. Credit: Matt Crawley

The Sandra J. Bromley scholarship is a full-tuition scholarship for undergraduate students in the College of Science. It provides in-state tuition, up to 15 credit hours per semester, for eight semesters which allows each recipient to complete their degree. The program, now celebrating its 10-year anniversary, is funded by the generosity of Ray Greer, BS’86, in Mathematics.

Each year, a freshman student is selected as a new Bromley scholar, and rolls into the program, while a senior student graduates. This unique model provides continuous funding to the students and allows the College of Science to assist and monitor the students as they progress through their academic program.

“The Bromley scholarship is extremely valuable because it can serve a student throughout their entire undergraduate career,” says Peter Trapa, dean of the College of Science. “The cumulative effect for the student is truly profound. Each year we see the incredible results.”

In addition, Greer and his wife, Jill, host the Bromley scholars at least once a year on campus. The informal luncheon allows the students to report on their progress and discuss any problems or concerns.

“I have had the pleasure of meeting and getting acquainted with the undergraduates as they progress through their academic goals, and it is always a pleasure to see their progression and academic interest flourish over time. In all I have done throughout my life, this has been one of the greatest and most rewarding experiences I have had the opportunity to be a part of,” says Greer.

Role Model

When Greer was just 12 years old, his mother, Sandra J. Bromley, moved her young family from Texas to Utah. The year was 1976. Bromley was promptly hired at the University of Utah and enjoyed a successful career as a technical illustrator in the College of Mines and Earth Sciences under the direction of Frank H. Brown.

“My mother was the single greatest influence in my life,” says Greer. “She taught me the value of hard work and perseverance. She also insisted that college was not optional. It was like going from junior high to high school — you just did it!”

Greer enrolled at the U for fall semester 1981 and was initially interested in computer science and engineering. However, computer science was highly competitive at the time so available classes were scarce.

“Fortunately, Hugo Rossi, a math professor, convinced me that if I majored in mathematics I could get as much course work in computer science as I wanted,” says Greer.

For several years Greer worked through the rigorous mathematics major requirements. He persevered and completed his math degree in 1986.

Then, in 2000, Greer’s mother moved back to Texas for the remaining years of her life. She passed away in 2011. Shortly thereafter, Greer established the Sandra J. Bromley scholarship to honor his mother by providing a way for deserving students to earn a college degree.

“She worked hard to provide for her family, but her greatest regret in life was not attending college herself, hence the vision behind the Bromley scholarship,” says Greer.

“Her requirement was that she would support me as long as I didn’t quit school,” says Greer.  “That is why the Bromley scholarship requires continuous attendance.”

Solving Problems

Greer has more than 40 years of experience in logistics and transportation industries. He has held senior management positions for Greatwide Logistics Services, Newgistics, Ryder Logistics and FedEx. He served as president of BNSF Logistics, headquartered near Dallas, Texas, from 2011 to 2018.

“Math allows me to think critically about situations and problems generally. Not just numerically but logically, to find patterns and trends that point to likely outcomes,” he says.

In 2018, Greer was named CEO of Omnitracs, a leading company in onboard technology for the transportation industry. Omnitracs is an international billion-dollar company that provides telematic devices and logistics to support drivers and their organizations to be compliant, safe and efficient.

“Math is universal and most importantly it teaches you discipline and persistence to work a problem until it is solved. That process of critical thinking and problem-solving has served me well throughout my entire career,” says Greer.

In 2021, Greer sold Omnitracs and transitioned to advisory board work as well as becoming an operating partner for Welsh, Carson, Anderson and Stowe, focused on supply chain technology investments.

Ray Greer has high hopes and expectations for today’s college students. His advice: “Connecting with people — not apps and cell phones — will differentiate you from the competition.”


The Bromley Scholars


Eliza Robert

“I love the entire vibe of the university”


Eliza Roberts is the most recent recipient of the Bromley scholarship. A freshman at the U, she is pursuing a degree in applied math and physics, with an emphasis in astronomy and astrophysics. Being awarded this scholarship has made Roberts’ experience at the U even more valuable. “It has truly allowed me to focus more on my classes, and even take classes that I wouldn’t have taken otherwise,” she says. “With the scholarship, I don’t have to worry about the financial aspects of college like I was fully intending to, which means that I can explore my passions and dedicate my time to learning.”

In addition to her hard work as a student, Roberts works as a math tutor in the TRIO office at the U. One of her proudest accomplishments is receiving her Girl Scout Gold award, for which she focused on creating a safe backyard space for adults with disabilities. 

Roberts lives in Salt Lake City and makes the most of her time at the U participating in LEAP classes, a year-long learning community for entering University students, and even discovering top-secret study and nap spots on campus. “I love the entire vibe of the university,” she says. “I feel safe, valued, and free. I have been able to explore myself more than I have in years, and it has helped me figure out who I want to be.”

~Julia St. Andre


Dannon Allred
“Space is simply beautiful”


Dannon Allred was awarded the Bromley Scholarship in 2021 and just completed his sophomore year at the U. A passionate learner, he is studying physics with an astronomy emphasis. “Ever since I’ve been interested in science, I’ve felt a pull towards physics and astronomy,” he says. “There’s just a lot in astronomy that spikes my curiosity, there’s a lot that’s unknown, and [outer] space is simply beautiful.”

The Bromley scholarship has given Allred the opportunity to experience college without any financial worries and has allowed him to focus more of his energy on his passion for astrophysics. “Obviously one of the most daunting things about college is paying for it, and that’s a lot of stress that most students have to deal with,” he says. “I would say that’s what’s most impactful about the Bromely scholarship because it allows me to go through college stress-free in that aspect.” 

On top of his astrophysics studies, Allred has been involved in several research projects on campus. “In my freshman year, I was part of Dr. Boehme’s … lab as part of the Science Research Initiative doing research on Organic Light-Emitting Diodes (OLEDs) using spintronics,” explains Allred. “This spring, I did an introductory research project analyzing the spectral emission features of the Sombrero Galaxy with Dr. Anil Seth” who specializes in astrophysics. 

Allred’s hope is to complete a graduate degree in the field as well. Not surprisingly, when he’s not busy studying stars and galaxies far, far away, he loves astrophotography, admiring the universe through the lens of his camera.   ~ Julia St. Andre


Michaela Fluck
“Proceeding Into the Wilderness”

Michaela Fluck works in the Zelikowsky Lab, which researches neural circuits that affect stress, fear, and social behavior. “I’ve always been interested in neurobiology, since I was a kid,” she states. “I’ve had family members who’ve had strokes and other brain injuries.”

A biology major with a psychology minor, Fluck says the study of abnormal psychology is also a passion of hers. “Seeing what can go wrong with the brain and what’s behind [it] …  is super interesting as well.”

Fluck was inspired to become a doctor by her patients at Primary Children’s Hospital, where she works as a phlebotomist. “I want to become an advocate for patients,” she says, “and help people work through the difficulties of medicine. Kids tend to hate procedures no matter what, so helping them work through the procedures is honestly one of the most rewarding things I’ve ever done.”

Her favorite class was organic chemistry. “Not a lot of pre-meds can say that,” she jokes. Fluck also loved taking an acting class at the U which relieved the stress of being a STEM student and harked back to her time as an actress in high school, especially her appearance in the the late Stephen Sondheim’s epic musical saga about daring to venture Into the Woods~ CJ Siebeneck


Keegan Benfield
Who knew I could do that?”

As a Bromley Scholar, Keegan Benfield BS’23, was able to spend more time on scientific passions, such as research and projects. “The Bromley Scholarship and the U have helped shape me to be the best that I can be.” 

Along with his double majors in mechanical engineering and physics, Benfield focuses his time on humanitarian efforts, volunteering with Youthlinc and Real life programs. He’s the president of the university’s marksmen club, and has attended National Collegiate events at the National and Junior level.

Prior to graduation, Benfield worked in the Deemyad Lab, researching condensed matter physics. The Lab focuses on theoretical physics, especially the physics of matter at extreme conditions of temperature and pressure.

One of Benfield’s favorite classes was Introduction to Relativity and Quantum Mechanics. “It was an ‘ah-ha!’ class that was challenging and fun,” Benfield says. “I have learned and expanded my knowledge in ways that amaze me. Who knew I could do that?”

Benfield recently completed a summer internship at Cosm and developed educational programs for planetariums using Digistar 7, which features full-dome programs and production services, giant screen films formatted for full-dome theaters, premium-quality projection domes, and theater design services. He plans on getting a master’s or PhD and work in a national laboratory or research company.   ~ CJ Seibeneck

 

View a LIst of all Bromley Scholars (as of June 2023) and brief updates on their whereabouts

Nobel winner Capecchi discovers new brain mechanism

The pandemic and its aftermath have raised anxiety to new levels. But the roots of anxiety-related conditions, including obsessive-compulsive spectrum disorder (OCSD), are still unclear.

In a new study, University of Utah Health scientists discovered insights into the importance of a minor cell type in the bra in — microglia —i n controlling anxiety-related behaviors in laboratory mice. Traditionally, neurons — the predominant brain cell type — are thought to control behavior.

The researchers showed that, like buttons on a game controller, specific microglia populations activate anxiety and OCSD behaviors while others dampen them. Further, microglia communicate with neurons to invoke the behaviors. The findings, published in Molecular Psychiatry, could eventually lead to new approaches for targeted therapies.

“A small amount of anxiety is good,” said Nobel Laureate Mario Capecchi, Ph.D., a distinguished professor of human genetics at the Spencer Fox Eccles School of Medicine at University of Utah and of biology in the School of Biological Sciences. He is also senior author of the study. “Anxiety motivates us, spurs us on, and gives us that extra bit of push that said, ‘I can.’ But a large dose of anxiety overwhelms us. We become mentally paralyzed, the heart beats faster, we sweat, and confusion settles in our minds.”

“This work is unique and has challenged the current dogma about the role of microglia function in the brain”

Capecchi, who arrived at the University of Utah in 1973 did much of his early research, leading to his Nobel Prize, at U Biology where a permanent display of his original equipment involving gene-targeting is housed.

Read the full story by Julie Kiefer about this exciting new research by Utah’s Nobel laureate in U of U Health.

Humans of the U: Katya Podkovyroff Lewis

Growing up as a military kid, my family moved a lot and friendships seldom lasted.

My French mother—a teacher and musician—encouraged reading and creativity while my American father —a soldier working in field artillery—encouraged tinkering and what he called “real world skills.” My curiosity was often left free to roam, and led me to have plenty of imaginary friends and daydreams that would occupy my time. As I grew older, this imagination mainly translated to creative writing.

Moving to the United States felt like a culture shock even as an American citizen, and high school was an even harder adjustment. When my senior year rolled around, I felt like a first-generation student in many ways with a father who had never been to college and a mother who wasn’t familiar with the American college system. Thanks to military educational benefits, I was able to attend American University in Washington, DC – my dream school and “reach school” due to my family’s financial situation. I took on double major in journalism and international studies, with a concentration in environmental sustainability and global health, intending to focus my career on science writing or science communication.

After graduation, I began a communications internship in January 2020 writing stories about climate change and ended up writing articles on COVID-19, specifically regarding resources for journalists and the toll of reporting on the pandemic. The pandemic changed a lot of people’s plans, including mine—when I was laid off from my restaurant job in March of 2020 and had the impending end of my internship that June, I scrambled for journalistic freelancing opportunities. But I wasn’t content with just writing about topics I was so interested in—I realized that I wanted to do the work. I decided to go back to college for a second bachelors in biology with a minor in Earth science at the University of Utah, where my passions have since flourished.

Read the rest of of Katya’s story in@theU.

Revisiting Carbon Offset Protocols

Revisiting carbon off-set protocols


When you walk through a forest, you are surrounded by carbon. Every branch and every leaf, every inch of trunk and every tendril of unseen root contains carbon pulled from the atmosphere through photosynthesis.

And as long as it stays stored away inside that forest, it’s not contributing to the rising concentrations of carbon dioxide that cause climate change. So it’s only natural that we might want to use forests’ carbon-storage superpower as a potential climate solution in addition to reducing human greenhouse gas emissions.

But climate change itself might compromise how permanently forests are able to store carbon and keep it out of the air, according to a new study led by University of Utah researchers. A study of how different regions and tree species will respond to climate change finds a wide range of estimates of how much carbon forests in different regions might gain or lose as the climate warms. Importantly, the researchers found, the regions most at risk to lose forest carbon through fire, climate stress or insect damage are those regions where many forest carbon offset projects have been set up.

“This tells us there’s a really urgent need to update these carbon offsets protocols and policies with the best available science of climate risks to U.S. forests,” said William Anderegg, study senior author and director of the U’s Wilkes Center for Climate Science and Policy.

The study is published in Nature Geoscience. Find an interactive tool showing carbon storage potential in forests in the U.S. here.

 

Read about a multi-perspective modeling approach and what we still need to know about climate offset protocols in our attempts to mitigate climate change in the full story by Paul Gabrielsen in @The U

 

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