Month: December 2024

AI: The Promise and Peril for the Planet

December 4, 2024

AI: The Promise and Peril for the Planet

Dec 04, 2024
Above: The AI image was generated using DALL·E.

For the past few decades, we have lived in the “Digital Age.” Now, we are stepping into a new one — the Age of AI.

While artificial intelligence (AI) has existed in primitive forms since the 1950s, it has now advanced to a readily accessible and ubiquitous state. Browser-based programs like ChatGPT are well-known, but they represent only a small portion of the scope, demands, capabilities and consequences of AI.

At its inaugural symposium last September at the University of Utah, the One-U Responsible AI Initiative invited over two hundred attendees, including researchers, university faculty, government officials, and industry leaders, to discuss the role and responsible usage of AI. Three key issues were addressed at the first panel of the symposium; the environmental impacts of AI, the dangers of AI-generated misinformation, and the application of AI for wildfire forecasting, an issue that poses challenges for the West’s electrical grid.

Resilience and sustainability

William Anderegg, director of the U-based Wilkes Center for Climate Science & Policy, is the executive committee member who leads the One-U RAI’s environmental working group. The group’s members bring their diverse expertise to establish ethical policy, explore AI’s impact on society and the environment, and develop responsible methods for using AI to improve climate research.

The working group’s vision is to utilize AI to bolster our resilience to climate change with collaboration, training, technology, and ethical governance.

AI for wildfire forecasting

Researchers, including Derek Mallia, research assistant professor of atmospheric sciences, have also utilized AI to forecast wildfires and its hazardous smoke.

“When you think of extreme weather, you think of hurricanes, tornadoes and so on. But one of the biggest causes of mortality is actually poor air quality,” said Mallia. “Wildfires cause a degradation in air quality during the summer, and these effects are becoming more widespread. We’re not just seeing smoke across the western U.S., but also in areas that traditionally don’t see a lot of wildfire smoke—parts of NewYork, for example.”

Read the full article by Ethan Hood in @TheU.

The intersection of science and aesthetics

December 4, 2024

The intersection of science and aesthetics

Dec 04, 2024

The work of recent chemistry graduate Uziel Gonzalez BS ‘24 was featured in the September 24 publication of C & E News feature “Chemistry in Pictures.” 

Uziel Gonzalez (BS ‘24)

Tom Richmond said for the C & E News “While purifying tert-butylmalononitrile, a useful starting material for the synthesis of organic electronic materials, University of Utah chemistry undergraduate Uziel Gonzalez discovered the molecule had made beautiful, fernlike crystals via room temperature sublimation. Though not suitable for structure determination by X-ray diffraction, which was the original goal, the crystals in the resulting 6 x 4 mm microscope image were suitable for framing. The acidic C–H bond of the malononitrile provides a useful handle to make new carbon-carbon bonds with highly fluorinated aromatics. 

Uziel Gonzalez is one of the 2024 Laya F. Kesner Award recipient. When he received the award, Professor Thomas Richmond noted, “Uziel was an outstanding student in Inorganic Chemistry, has been involved with the ACS student affiliate's group and even managed to make some new fluorocarbon molecules in my lab. Ultimately, he would like a career as an FBI Agent."  

The feature “showcases the beauty of chemistry, chemical engineering and related sciences” to the 150,000 readers of C&E News and beyond.  As noted in the article, an elegant leaf-like structure was formed upon sublimation of a volatile organic compound.  Although not suitable for crystallography, it was suitable for framing. 

This story was originally posted on @chem.utah.edu  where you can see other stunning images from Uziel Gonzalez 's collection.

The surprising role of CO₂ in cellular health

December 2, 2024

The surprising role of CO₂ in cellular health

Dec 02, 2024

The cells in our bodies are like bustling cities, running on an iron-powered system that uses hydrogen peroxide (H₂O₂) not just for cleaning up messes but also for sending critical signals.

Normally, this works fine, but under stress, such as inflammation or a burst of energy use, oxidative stress damages cells at the genetic level.

This is because iron and H₂O₂ react in what’s known as the Fenton reaction, producing hydroxyl radicals, destructive molecules that attack DNA and RNA indiscriminately. But there’s a catch. In the presence of carbon dioxide — that pesky gas disrupting global climate systems — our cells gain a secret weapon in the form of bicarbonate which helps keep pH levels balanced.

A team of University of Utah chemists has discovered that bicarbonate doesn’t just act as a pH buffer but also alters the Fenton reaction itself in cells. Instead of producing chaotic hydroxyl radicals, the reaction instead makes carbonate radicals, which affect DNA in a far less harmful way, according to Cynthia Burrows, a distinguished professor of chemistry and senior author of a study published this week in PNAS.

“So many diseases, so many conditions have oxidative stress as a component of disease. That would include many cancers, effectively all age-related diseases, a lot of neurological diseases,” Burrows said. “We’re trying to understand cells’ fundamental chemistry under oxidative stress. We have learned something about the protective effect of CO₂ that I think is really profound.”

Co-authors include Aaron Fleming, a research associate professor, and doctoral candidate Justin Dingman, both members of the Burrows Laboratory.

“Just like opening up a can of beer. You release the CO₂ when you take your cells out of the incubator. It’s like doing experiments with a day-old glass of beer. It’s pretty flat. It has lost the CO₂, its bicarbonate buffer,” Burrows said. “You no longer have the protection of CO₂ to modulate the iron-hydrogen peroxide reaction.”

She believes bicarbonate needs to be added to ensure reliable results from such experiments.

Read the full article by Brian Maffly in @TheU.

Exploring the Vulnerabilities of Endangered Birds

December 2, 2024

Exploring the Vulnerabilities of Endangered Birds

Dec 02, 2024
Above: Kyle Kittelberger( a graduate student in the School of Biological Sciences) at a bird banding station in northeastern Turkey holding a steppe buzzard. Courtesy Kyle Kittelberger.

Looking to inform the conservation of critically endangered bird species, University of Utah biologists completed an analysis identifying traits that correlate with all 216 bird extinctions since 1500.

Species most likely to go extinct sooner were endemic to islands, lacked the ability to fly, had larger bodies and sharply angled wings, and occupied ecologically specific niches, according to research published this month.

While some of these findings mirror previous research on extinct birds, they are the first to correlate bird traits with the timing of extinctions, said lead author Kyle Kittelberger, a graduate student in the School of Biological Sciences.

“I’ve been very interested in extinctions and understanding the species that we’ve lost and trying to get a sense of how we can use the past to better inform the present and future,” said Kittelberger, who is completing his dissertation on how the bodies and wings of certain species of migratory songbirds have changed in response to climate change.

Connecting bird traits with species extinction

His team’s analysis tapped into BirdBase, a dataset of ecological traits for the world’s 11,600+ bird species compiled by U biology professor Çağan Şekercioğlu and the Biodiversity and Conservation Ecology Lab at the U. The team simultaneously analyzed a broad range of biogeographical, ecological and life history traits previously associated with extinction and extinction risk for bird species that have gone extinct as well as those that lack recent confirmed sightings and have therefore disappeared.

One in eight species is in peril

This timing coincides with the rise of scientific observation, resulting in a systematic documentation of plant and animal life. It is also the time when European exploration took off, leading to the disruption of ecosystems around the globe as a result of colonization and introduced species.

Today, 1,314 bird species are at risk of extinction, according to the IUCN Red List of Threatened Species, or about 12% of the total.

Many species, such as the ‘Akikiki (Oreomystis bairdi), endemic to the Hawaiian island of Kauai, are so rare that they are functionally extinct. Kittelberger photographed the pictured ‘Akikiki, also called Kauai’s creeper, in the Alaka‘i Wilderness Preserve in 2022, when it was believed around 70 or so remained in the wild; today, only one individual remains.

As with many other Hawaiian bird species, the main threat to the ’Akikiki comes in the form of introduced species, principally malaria-carrying mosquitoes and habitat-wrecking livestock, according to Hawaii’s Division of Forestry and Wildlife.

Read the full article by Brian Maffly in @TheU.