Bill Jack

Bill Jack’s undergraduate experience at the University of Utah’s Chemistry Department was foundational and flavored his graduate school and professional path. In hindsight, Bill also recognizes the influence of the few humanities courses he participated in where discussions on James Joyce and American Literature altered his perspective on the world. His only regret about his undergraduate years here at the U, is that he did not slow down and take advantage of broader educational opportunities to learn as much as he could in both the humanities as well as in chemistry.

During one undergraduate summer, Bill was inspired by a single sentence in a physics course that would influence the way he approached the world. The instructor, Dr. Swaggart, began his class by telling the students, “I’m going to teach you about a new way to look at the world.” Bill integrated this sentiment in a variety of different subjects since then, whether in math, social studies, literature, chemistry, anything really. “It’s a different way to see the world, and that broad background just increases your appreciation of the world,” says Bill.

Bill’s educational foundation lead him to a graduate program at Duke University where he thought he would begin a career as a physical biochemist after “tailing” Sidney Velick all summer, but, in an effort to simplify his newlywed life, he asked to work in a lab which quickly altered his path. He ended up being a graduate student with Paul Modrich researching an enzyme that ended up being one of the enzymes that is foundational at New England Biolabs--the only “real” job he’s ever had after he completed his graduate and postdoc work.

Bill has been working at NEB for the past 31 years, and now enjoys the freedom to take risks in his research. He confirms that the company’s founder is absolutely right when he claims that, “New England Biolabs scientists can’t wait to get to work each morning to see how their experiments turned out.” Bill’s latest project is admittedly risky, but that’s what makes it so exciting. The possibility that something might work as he tries to wrap his mind around different ways of analyzing and changing the environment to find a solution for such a fascinating biological phenomena keeps him pushing new boundaries.

Bill is collaborating with a team at Columbia University with an expertise in the biology of the DNA sequence he’s investigating. They’re growing, breaking, and piecing back together the sequences to try to replicate in a test tube the DNA splicing that happens naturally. “I believe that there will be steps along the way that we will have insights into other organisms, other processes whether they be normal ones or ones that cause disease, and there’s also even prospects from a commercial perspective that some of the enzymes involved will be useful in advancing other molecular biology techniques. The company I work for takes enzymes that occur in nature, pulls them out, and characterizes them so they’re available in other workflows to prepare DNA sequences.”

 
by Anne Vivienne
 

Kurt Zilm

As Yale’s current Chair of the Chemistry Department, it seems clear that Kurt has always understood what the foundation of a successful chemistry department is built on: human connection, collaborative research, and investment in students. As a graduate student at the University of Utah, Kurt took advantage of Professor Ted Eyring’s time, knowledge, and generosity as much as Ted would endure his endless questions and curiosity. He’s spent the past 16 years as the Director of Undergraduate Studies at Yale University, and has committed to create an environment for students that allows them to indulge their curiosity--just as he was able to do with Professor Eyring.

After being at Yale for 38 years, Kurt has recently been part of a renaissance in their college of science as they renovate and build facilities that give all students the opportunities and experiences they need in order to establish themselves as serious chemists and innovators. The department’s investments have made it possible for every undergraduate in organic chemistry to have their own hood with an updated condenser system that delivers chilled water back through a seperate gravity-fed drain system--saving 150,000 gallons of water per year. Kurt has moved his lab three times in the past few years with all the renovating, but of course, is already seeing the extensive benefits to student research.

Since 1995, Yale has made a big push to provide more opportunities for women, minority, economically underprivileged, and other historically underrepresented students in STEM through their STARS Program. Zilm has seen the impact of this program on the science community, and the stats reveal that students who participate in this program continue on in the sciences with a significant impact.

Kurt’s own research is on the cusp of exciting results that he will be publishing in the near future. For one project, he’s been collaborating with a team at Dartmouth trying to figure out what it is that makes infectious prions infectious and how to differentiate them from non-infectious prions. He’s also been working with a team at Yale’s Medical School to understand the molecular mechanism of Alzheimer’s Disease--which he thinks they now understand, and have drugs that seem to work with mice.

These research projects have been 90% of Kurt’s work over the past five years, and it’s all finally starting to bear some fruit. He is quick to talk about the importance of collaboration:

“These projects are really starting to bear fruit only because we’re collaborating with these two teams, and we have the right people and the right facilities to work on this. None of us could have done it on our own.”

For Zilm, it’s all connected: from the similar molecular origins of his two projects, to the investment in students and facilities, to his beginnings at the University of Utah, and the collaborations he’s been part of in the past, present, and future.

 
by Anne Vivienne
 

50th Anniversary

GOLDEN Anniversary
1970-2020


July 1, 2020, marks the 50-year anniversary of the College of Science, comprised of the School of Biological Sciences, and Departments of Chemistry, Mathematics, and Physics & Astronomy.

A Brief History

Henry Eyring

When the University of Deseret was founded in 1850 in the Territory of Utah, it was primarily a training school for teachers. The newly formed university taught only a handful of topics, including algebra, astronomy, botany, chemistry, geometry, and zoology. Indeed, mathematics and physical sciences were well represented from the earliest days of the university.

By the 1920s, only six organized schools existed at the U: Arts and Sciences, Business, Education, Engineering and Mines, Law, and a two-year Medical School.

James M. Sugihara, PhD 1947

Between 1948 and 1958, through two reorganizations, the School of Arts and Sciences expanded to become the College of Letters and Science. However, the composition was enormous, including departments of air science, anthropology, botany, chemistry, English, experimental biology, genetics and cytology, history, journalism, languages, mathematics, military science and tactics, naval science and tactics, philosophy, physics, political science, psychology, sociology, speech and theater arts, and zoology.

By the late 1960s, Pete D. Gardner, a prominent organic chemist at the U, had convinced the central administration that mathematics and physical sciences would be most effective if separated from the large, amorphous College of Letters and Science.

Therefore, on July 1, 1970, the College of Letters and Science was replaced by three new colleges: Humanities, Social and Behavioral Science, and the College of Science.

The disciplines of biology, chemistry, mathematics, and physics and astronomy were ideally consolidated in one cohesive academic unit. Gardner was appointed as the first dean of the College and served from 1970 to 1973.

The College of Science utilized seven buildings in 1970, including Chemistry (the north wing was finished in 1968), South Biology (completed in 1969), North Biology (the James Talmage Building), Life Sciences (built in 1920 and former home the of School of Medicine), the John Widtsoe Building (housed both the chemistry and the physics departments), the James Fletcher Building and South Physics. The total faculty consisted of about 80 tenured or tenure-track professors across all four departments.

Modern Day Powerhouse

Today the College of Science is one of the largest colleges within the University of Utah, offering undergraduate and graduate degrees in biology, chemistry, mathematics, and physics and astronomy, plus specialized degrees such as a doctorate in chemical physics.

The College supports nearly 2,000 undergraduate science majors and 475 graduate students and employs 143 full-time tenured or tenure-track faculty. The College also employs hundreds of adjunct and auxiliary faculty, postdoctoral fellows, research assistants, lab technicians, and support staff.

Last year, the College received about $36 million in external research funding, which is nearly seven percent of the University’s total external research revenue.

“The exceptional caliber of the College’s faculty has been a driving force behind the University’s ascension as a world-class research university,” says Peter Trapa.

The College has constructed new educational and research facilities in recent years, including the Thatcher Building for Biological and Biophysical Chemistry and the Crocker Science Center on Presidents Circle. The two buildings combined serve thousands of students each year with professional academic advising, expanded classrooms, and cutting-edge labs and instrumentation.

This year, a new project–the Stewart Building for Applied Sciences – was approved by the Utah legislature to renovate the historic William Stewart building and construct a 100,000 square-foot addition to house the Department of Physics & Astronomy and the Department of Atmospheric Sciences.

The proposed Applied Sciences Center will be 140,729 square-feet in size, consisting of 40,729 square feet of renovated space and 100,000 square feet of new construction. Undergraduate teaching labs, research labs, and classrooms will comprise 90% of the footprint and faculty offices will use 10% of the space. The new facility will support more than 40 faculty members, 200 undergraduate majors, 115 graduate students, and nearly 5,000 students taking STEM courses each year at the U.

Building the Future

As the 21st century unfolds amidst a global pandemic, the importance of science and mathematics will only continue to increase.  Our quality of life and economic future depends on the next generation of scientists. The College of Science is refreshing its strategic plan to further strengthen and enhance its academic and educational programs and its scientific leadership in the nation. Emerging priorities include:

  • Fully implement the Science Research Initiative (SRI) in the Crocker Science Center to serve 500 undergraduates per year with specialized research opportunities.
  • Establish new endowed faculty chair positions in each department, and increase the number of endowed professorships and graduate fellowships.
  • Continue to increase the amount of external research funding received in the College per year.
  • Invest in new and existing research directions to strengthen the College’s faculty.
  • Continue to advance our commitment to diversity, and foster inclusive communities of faculty, staff, and students.
  • Increase the six-year graduation rate of declared Science majors, and increase the total number of STEM graduates at the University.

Pearl Sandick, Associate Dean for Faculty Affairs, has led an effort that has distilled the input of faculty, staff, and students into a coherent plan for the future.

“The College will be prepared to meet the demands of the next 50 years in science education and research,” says Sandick. “We will see our way through the current crisis,  with an enhanced focus and commitment to student success, providing the facilities and rigorous training needed to boost the number of STEM graduates in Utah.”

The College is sincerely grateful for its numerous friends and supporters over the last 50 years. Each gift, large and small, propels the College forward. Please join us to write the next chapter, and the following 50 chapters, in the College of Science.   

Goldwater Winner

Lydia Fries

Lydia Fries awarded prestigious Goldwater Scholarship.

The College of Science is pleased to announce that Lydia Fries has been awarded a Goldwater Scholarship for 2020-21.

As a junior in chemistry, Lydia intends to obtain a Ph.D. in either organic chemistry or electrochemistry. She has done research in both Matt Sigman’s and Shelley Minteer’s groups, and Lydia is an author on two papers with both professors. She has worked on a variety of projects involving electrochemistry, palladium catalysis, and computationally focused projects. As an undergraduate she enrolls in many graduate-level courses and is a Teaching Assistant for Organic Spectroscopy I. Lydia was accepted to REU programs this summer, but has committed to an internship at Genentech and hopes that the current pandemic will have subsided by the time her internship is to begin mid-May.

With encouragement from high school teachers, Lydia followed her passion and her strong aptitude for STEM subjects, and ignored the warnings from her broader community that she shouldn’t pursue such an expensive and “useless” degree. She followed her heart and her brain to the University of Utah where she landed in the ACCESS program and was immediately surrounded by many intelligent and motivated women.

In addition to her studies, Lydia enjoys rock climbing and spending time outdoors, and is currently staying at safe at home in St. George.

The Goldwater Scholarship

As the result of a partnership with the Department of Defense National Defense Education Programs (NDEP), Mrs. Peggy Goldwater Clay, Chair of the Board of Trustees of the Barry Goldwater Scholarship and Excellence in Education Foundation, announced that the Trustees of the Goldwater Board have increased the number of Goldwater scholarships it has awarded for the 2020-2021 academic year to 396 college students from across the United States. “As it is vitally important that the Nation ensures that it has the scientific talent it needs to maintain its global competitiveness and security, we saw partnering with the Goldwater Foundation as a way to help ensure the U.S. is developing this talent,” said Dr. Jagadeesh Pamulapati, Director of the NDEP program, as he explained the partnership. With the 2020 awards, this brings the number of scholarships awarded since 1989 by the Goldwater Foundation to 9047 and a scholarship total to over $71M.

From an estimated pool of over 5,000 college sophomores and juniors, 1343 natural science, engineering and mathematics students were nominated by 461 academic institutions to compete for the 2020 Goldwater scholarships. Of students who reported, 191 of the Scholars are men, 203 are women, and virtually all intend to obtain a Ph.D. as their highest degree objective. Fifty Scholars are mathematics and computer science majors, 287 are majoring in the natural sciences, and 59 are majoring in engineering. Many of the Scholars have published their research in leading journals and have presented their work at professional society conferences.

Goldwater Scholars have impressive academic and research credentials that have garnered the attention of prestigious post-graduate fellowship programs. Goldwater Scholars have been awarded 93 Rhodes Scholarships, 146 Marshall Scholarships, 170 Churchill Scholarships, 109 Hertz Fellowships, and numerous other distinguished awards like the National Science Foundation Graduate Research Fellowships.

 

The Goldwater Foundation is a federally endowed agency established by Public Law 99-661 on November 14, 1986. The Scholarship Program honoring Senator Barry Goldwater was designed to foster and encourage outstanding students to pursue research careers in the fields of the natural sciences, engineering, and mathematics. The Goldwater Scholarship is the preeminent undergraduate award of its type in these fields.

 

by Anne Marie Vivienne,
Chemistry News - 03/30/2020

Electrochemistry

Henry S. White - A Positive Force in Electrochemistry

 

Henry S. White

From energy storage and generation to nanoscale 3D battery architectures to the transport of drugs through human skin, Henry White’s research is pioneering and highly imaginative within the field of electrochemistry. His work on nanoscale electrochemistry was groundbreaking and has developed into a significant field of research with various applications. Professor of Chemistry Shelley Minteer commented that White “greatly enjoys complex problems and is the electrochemist to go to when you have complex mass transport phenomena to understand.”

There’s an obvious reason why Henry White is considered one of the most influential and innovative electrochemists of his generation: he wears his passion and thoroughness for research on his sleeve. White maintained a strong research group funded by the National Institutes of Health, National Science Foundation, the Department of Energy, and the Department of Defense while serving for six years as Chair of the Department of Chemistry, then five years as Dean of the College of Science. His administrative service was a commitment back to an institution that allows him to do what he loves most: teaching and research.

Henry S. White

Now that he can once again devote all of his time to research and teaching, White is thrilled to be immersed in the frontiers of electrochemistry—asking relevant and innovative questions for our generation’s complex problems. As the Widtsoe Presidential Chair, he continues to train postdoctoral fellows, undergraduates, and graduate students in electrochemistry. The Widtsoe Chair specifically is valuable in providing funding for students to do high risk and truly innovative research that they wouldn’t otherwise be able to do.

“There are a lot of great questions” in the field of electrochemistry says White. Research isn’t just about solving a problem, it’s about learning how to ask interesting and original questions—something White finds a lot of joy in doing.

“Electrochemistry is a fascinating area of science, and a very diverse area, comprising many fundamental research topics in chemistry, materials science, physics, and engineering. It is also extremely relevant in providing potential solutions to many problems that society faces, especially in providing means for developing sustainable energy sources. I’ve been very fortunate during my career to have had the necessary funding and resources to work on very basic science questions in this area. And I’ve been even more fortunate to be able to work with incredibly talented students and postdocs at the University of Utah, many who have continued to work on electrochemical problems in both industry and academics.”

Dr. Hang Ren, a former postdoc of White’s who is now an Assistant Professor at Miami University in Ohio, focused on electrical measurements on individual DNA molecules trapped inside a protein nanopore while training with White. They were able to trap a single DNA molecule for hours, and watch its motional dynamics, and monitor chemical reactions via the change in electrical current through the protein.

In a second research project, they used platinum electrodes with radii as small as 5 nanometers to measure the nucleation rates of bubbles. They were able to generate a single nanobubble at the electrode surface, measure the nucleation rate, and infer the geometry of the smallest stable bubble that contained as few as 25 molecules. “This is a fundamentally important problem in the field of electrocatalysis, where bubbles are often formed and disrupt the catalytic processes on the electrode,” says Professor Ren.

Dr. Rui Gao, Dr Henry S. White, & Dr Koushik Barman.

White trains his students and postdocs on how to be a researcher, to ask innovative questions, and to be relentlessly rigorous in their approach. As he works with undergraduate and graduate students as well as postdocs, his methods are significantly influencing the next generation of scientists to continue a legacy of research excellence. After training with White for years, Professor Ren affirms that “Henry’s research approach is very  unique. In addition to solving scientific problems  elegantly, he is especially great at asking fundamental scientific questions. He is also highly innovative and very good at exploring new directions in electrochemistry. I was greatly influenced by my postdoc training with him.”

Henry White’s research is often cited by other researchers and is foundational in the fields of electrochemistry and analytical chemistry. “Henry has an uncommon disposition for innovation in undertaking both experimental and theoretical challenges in his research,” says Joel Harris, Distinguished Professor of Chemistry. White’s research has been recognized in major awards from the Society of Electroanalytical Chemistry, the Royal Society of Chemistry, the ACS Division of Analytical Chemistry, and the Electrochemical Society. He is also a Fellow of the American Academy of Arts and Sciences, the American Chemical Society, and the American Association for the Advancement of Science.

 - by Anne Marie Vivienne
  First Published in Discover Magazine, Fall 2019

 

Jim Sugihara

“I have lived by the principle that one ought to give back more than they receive.” - Jim Sugihara

 

James M. Sugihara, first Ph.D. recipient at the University of Utah and long-time faculty member in Chemistry, passed away on Nov. 12, 2019. He was 101.

Jim Sugihara, 1947

Sugihara holds an important place in the University’s history, as well as Utah’s history.

In 1942, shortly after the bombing of Pearl Harbor, when Sugihara was just 24, he and his family were relocated from California to the Topaz Mountain internment camp in central Utah. The family lost their home and business.

However, Sugihara was granted a leave from Topaz Mountain to pursue an education, since he had already earned a bachelor’s degree in chemistry at UC-Berkeley in 1939. He enrolled at the U in 1944 and studied chemistry with professor Henry Eyring.

In 1946, Sugihara’s 84-page Ph.D. dissertation on “The Reactions of Mercaptans on Sucrose and Molasses,” included only three approval signatures: Walter D. Bonner, Lloyd E. Malm and Elton L. Quinn. (Henry Eyring had not yet started work as dean of the Graduate School by that date.)

May and Jim Sugihara, 1964

Sugihara received his doctorate degree in Chemistry in 1947. The University catalog in 1948-1949 then listed the following chemistry faculty: professors Elton Quinn, Lloyd Malm, and Henry Eyring; associate professors Vic Beard, Randall Hamm, Bill Burke, Jim Horton; and assistant professors Stuart Haynes, George Hill, Austin Wahraftig, Ransom Parlin, Bruno Zwolinski, and James Sugihara.

 

“Scientific progress has moved in ways that one could not expect. Research in genetics has become paramount, leading to improvements in medicine and human health that one could not imagine just 10 or 20 years ago.”

- Jim Sugihara at 100 years of age

 

In 1964, Sugihara moved to North Dakota State University and became dean of the College of Science and Mathematics. He was named Dean of the Graduate School and Director of Research in 1974. In 1998, he retired as Professor Emeritus.

In 2010, the James M. Sugihara Scholarship – a permanent named scholarship – was established in the Chemistry Department at the U. It provides financial support for an undergraduate who is studying chemistry and who is living on campus in the Crocker Science House located on Officers Circle in Fort Douglas.

 

Sugihara with scholarship winners Shwan Javdan and Elizabeth Fine

Staff: James Muller

Staff Excellence Award


 

The College of Science is pleased to announce that James Muller has received an inaugural College of Science Staff Excellence Award in 2019. The Staff Excellence Awards were created this year to recognize the impactful contributions from staff in the College and will be an ongoing award in the future.

Jim is the Director of Chemistry’s Mass Spectroscopy Laboratory, and he oversaw construction of the Thatcher Chemistry Building for Biological and Biophysical Chemistry, and the Crocker Science Center. Both individuals have demonstrated an outstanding level of commitment to the educational and research missions of the College of Science for many years.

The College of Science has many truly wonderful staff who work tirelessly to assist students and faculty. Our sincerest thanks to this group for taking the initiative each day to make the College excellent in so many different ways!

 

Rachel Cantrell

2019 Goldwater Recipient


A 2019 Goldwater Scholarship has been awarded to Rachel Cantrell, a junior majoring in chemistry.

Cantrell has maintained a near perfect GPA while working in professor Ryan E. Looper's laboratories on orthogonal projects. She lists her mentors as, Stefan Schulz, Ryan LooperJon SegerMatthew NelliMarkus MenkeChelsea HarmonCody Bender, and Autumn Amici.

Rachel plans to pursue a Ph.D. in Organic Chemistry, with the overall goal of becoming a research and teaching professor.
 

THE GOLDWATER SCHOLARSHIP


As the result of a partnership with the Department of Defense National Defense Education Programs (NDEP), Mrs. Peggy Goldwater Clay, Chair of the Board of Trustees of the Barry Goldwater Scholarship and Excellence in Education Foundation, announced that the Trustees of the Goldwater Board have increased the number of Goldwater scholarships it has awarded for the 2020-2021 academic year to 396 college students from across the United States. “As it is vitally important that the Nation ensures that it has the scientific talent it needs to maintain its global competitiveness and security, we saw partnering with the Goldwater Foundation as a way to help ensure the U.S. is developing this talent,” said Dr. Jagadeesh Pamulapati, Director of the NDEP program, as he explained the partnership. With the 2020 awards, this brings the number of scholarships awarded since 1989 by the Goldwater Foundation to 9047 and a scholarship total to over $71M.

From an estimated pool of over 5,000 college sophomores and juniors, 1343 natural science, engineering and mathematics students were nominated by 461 academic institutions to compete for the 2020 Goldwater scholarships. Of students who reported, 191 of the Scholars are men, 203 are women, and virtually all intend to obtain a Ph.D. as their highest degree objective. Fifty Scholars are mathematics and computer science majors, 287 are majoring in the natural sciences, and 59 are majoring in engineering. Many of the Scholars have published their research in leading journals and have presented their work at professional society conferences.

Goldwater Scholars have impressive academic and research credentials that have garnered the attention of prestigious post-graduate fellowship programs. Goldwater Scholars have been awarded 93 Rhodes Scholarships, 146 Marshall Scholarships, 170 Churchill Scholarships, 109 Hertz Fellowships, and numerous other distinguished awards like the National Science Foundation Graduate Research.

The Goldwater Foundation is a federally endowed agency established by Public Law 99-661 on November 14, 1986. The Scholarship Program honoring Senator Barry Goldwater was designed to foster and encourage outstanding students to pursue research careers in the fields of the natural sciences, engineering, and mathematics. The Goldwater Scholarship is the preeminent undergraduate award of its type in these fields.

Distinguished Research

“Since Professor Molinero joined the Department of Chemistry as Assistant Professor in 2006, she has developed a thriving research program in physical and materials chemistry, with foci on elucidating the phase behavior of water and its impact on atmospheric processes, and the design of new materials for energy and cryopreservation. Professor Molinero’s ground breaking research at the University of Utah has already resulted in over 290 presentations at conferences, universities, and research institutions all over the world (110 of them by students and postdocs of Molinero), and 95 journal articles—including three in Nature—that have gathered almost five thousand citations,” said one nominator.

“Professor Molinero’s work is a hallmark of what research and scholarship at our University should be about. In her 12 years of independent research, she has made an indelible mark in several fundamental areas of physical and computational chemistry, with implications that extend to atmospheric sciences and the design of materials for energy and catalysis. Professor Molinero is a leader in the Chemistry and Physics communities. She is the Vice-chair and Chair-elect of the Theory subdivision of the American Chemical Society, member of the nominating committee of the Division of Chemical Physics of the American Physical Society, member of the Board of Managers of the American Institute of Physics Publishing, the Editorial Advisory Board of the Journal of Chemical Physics and of The Journal of Physical Chemistry, has been on the selection committee of major awards by the American Chemical Society…”